**Introduction: Why the Last Dose Missions Matter**

Have you ever found yourself playing GTA V, cruising through Los Santos, and then getting the itch to try something new? If you’re a fan of Rockstar’s more recent content updates, you’ve probably heard about the “Last Dose Missions” in GTA V Online. These missions promise a thrilling mix of action, mystery, and—of course—more chances to make money. But the real question is: *How do you even start them?*
If you’re scratching your head right now, don’t worry. We’re going to break it all down in this simple guide, so you can get into the action without any hassle.
**The Problem: Why It’s Not As Easy As You Think**
You might be asking yourself, “Why is starting these missions so tricky? What’s the deal?” Well, unlike some of the simpler missions in GTA V, the “Last Dose Missions” require a bit more effort to get going. It’s not as simple as just picking up a phone call or heading to a new marker on the map.
For one, you have to have completed the entire “The First Dose” series of missions. That’s right. No skipping ahead, no shortcuts. If you haven’t finished that first batch, the game won’t let you dive into the Last Dose Missions. It’s like trying to get into a club without an ID—you’ve got to have your dues paid first.
**The Solution: How to Start the Last Dose Missions**
So, how do you actually get started with the Last Dose Missions? It’s easier than it sounds—promise!
1. **Complete “The First Dose” Missions**
Like we said earlier, before you can get started with the Last Dose, you need to finish the previous missions in the series. These are part of the “The Last Dose” update in GTA Online and set the stage for the more intense challenges ahead. Once you’ve completed them, you’ll be ready for the next step!

2. **Check Your Phone**
After finishing “The First Dose” missions, you’ll receive a call or a text from Dr. Isiah Friedlander (yes, the one with the suspiciously eccentric behavior). He’ll give you the lowdown on what’s coming next. This call will unlock the “Last Dose” missions, so make sure your in-game phone is ready for action.
3. **Look for the Mission Markers**
Once you’ve gotten that phone call, mission markers will appear on your map. Head to these locations to begin the journey into the Last Dose. It’s like opening a new chapter of your favorite book—full of excitement, but also a little mysterious.
4. **Make Sure You’re Ready for Action**
These missions aren’t for the faint of heart. They involve a mix of high-intensity combat, tricky objectives, and some truly bizarre moments. Make sure you’ve got the right equipment, weapons, and supplies before you jump in. Trust us, you’ll thank yourself later.
**Player Feedback: What Are Others Saying?**
The response from the GTA V community has been mixed, as expected. Some players enjoy the extra challenge, while others feel a little frustrated by the requirements. Here’s a sneak peek at what people are saying:
– **User A**: “I spent way too long trying to figure out why I couldn’t start the missions. Turns out I missed one small thing in the previous missions. Definitely frustrating, but once I finally got going, it was so worth it!”

– **User B**: “I like the new content, but the missions felt a bit repetitive. That said, they were still fun with friends. Make sure to team up if you want to survive some of the crazier parts.”
– **User C**: “The phone call from Dr. Friedlander felt a little out of nowhere, but I guess that’s GTA for you. I love how weird the Last Dose missions are. Definitely a lot of surprises along the way.”
So, it seems like most players are enjoying the missions once they get started, but the confusion around how to begin is a real pain point.
**Interactive Question: What’s Your Experience?**
Have you run into any issues while starting the Last Dose missions? Maybe you’ve discovered a clever workaround or something that worked better for you? Don’t be shy—share your tips and tricks in the comments below. We’d love to hear how you tackled the challenge!
**Summary: Get Ready to Take on the Last Dose Missions**
In conclusion, the Last Dose Missions are a fun and exciting addition to GTA V, but starting them can be a little tricky if you’re not prepared. Remember, complete the First Dose missions, get that all-important phone call from Dr. Friedlander, and then head to the mission markers. With the right prep, you’ll be in for an unforgettable ride!
Happy gaming, and don’t forget to pack your best weapons!